Adenomatoid odontogenic tumor (AOT), a benign (hamartomatous) lesion of odontogenic origin, is an uncommon tumor which affects mainly. Adenomatoid odontogenic tumor (AOT) is a rare odontogenic tumor which is often misdiagnosed as odontogenic cyst. To acquire additional. Adenomatoid odontogenic tumor is a hamartomous benign neoplasia of odontogenic origin. It appears mostly in young patients and females, the maxillary.

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It is the fourth most common odontogenic tumor which is benign, slowly growing and has three variants, follicular, extrafollicular, and peripheral. In tooth impactions next to the alveolar ridge, the tumor could occasionally involve the gingiva during or after the eruption process, which would justify the peripheral variant. The adenomatoid odontogenic tumor is an odontogenic tumor [1] arising from the enamel organ or dental lamina.

They are treated conservatively by curettage and enucleation as both are benign in nature. Adenomatoid odontogenic tumor The adenomatoid odontogenic tumors presented epithelial proliferation in which cells placed in solid nodules forming sheets, or a nest-and cord-like pattern.

Biological profile based on cases. A case report of the literature. Acta Pathol Microbiol Scand. J Oral Maxillofac Pathol ; Bull Tokyo Dent Coll.

This justifies the expression in all epithelial cell elements of other AOTs and odpntogenic the REE, regardless of the histological characteristics.

Adenomatoid Odontogenic Tumor arising from the manidibular adenomatid region: But in our case presented, the presence of unilocular cystic lesion, fluid on aspiration, and cystic cavity on adenomstoid has to some extent support the terminology adenomatoid odontogenic cyst AOC as termed by Marx and Stern. Footnotes Source of Support: The underlying connective tissue was fibrous, thick, with extensive areas of hemorrhage and discrete inflammatory mononuclear infiltrate.


AOT has three variants, follicular, extrafollicular, and peripheral. Interspersed in the solid areas, as if separating them in blocks, there were fusiform and stellated cells resembling the stellate reticulum with thin strands. Immunohistochemical detection and distribution of enamelysin MMP in human odontogenic tumors.

Adenomatoid odontogenic tumor, an uncommon tumor

The tumor was slowly growing within sixteen months; it filled the canine socket after extraction and expanded buccally to fill the buccal fold. Few cases of AOT, like this case, were described in the literature in association with a maxillary lateral incisor. Report of a case with peculiar features.

Usually, they do not exceed cm in diameter. This article has been cited by other articles in PMC. But more than one tooth adenomwtoid also be related with AOT as noticed in our case analysis wherein permanent incisors, canines, and premolars were involved with the lesion.

Adenomatoid odontogenic tumor – Wikipedia

After considerations about pathogenesis, the authors suggested that the nature of AOT is hamartomatous with histogenesis from the reduced enamel epithelium. This paper reported a case of AOT, in a year-old female, associated with an impacted maxillary left lateral incisor. On radiographsthe adenomatoid odontogenic tumor presents as a radiolucency dark area around an unerupted tooth extending past the cementoenamel junction.


Radiographs will exhibit faint flecks of radiopacities surrounded by a radiolucent zone. Oral and Maxillofacial Pathology.

The continuous slow growth of the lesion may cause cortical plate expansion leading to a painless hard swelling, asymmetry of the face, and displacement of the teeth, as was evident in our case analysis. Still the search for accurate classification and ideal nomenclature for AOT continues.

Differential diagnosis Dentigerous cyst. Salvage of an impacted canine associated with anadenomatoid odontogenic tumour: As the AOT is an epithelial tumor, it is interesting to analyze histochemically the different types of cytokeratins in it. Adenomatoid odontogenic tumor AOT is a rare wdenomatoid tumour that is frequently misdiagnosed as odontogenic cyst. Author information Copyright and License information Disclaimer.

Mandibular adenomatoid odontogenic tumor: Radiographic and pathologic correlation

Expression of cytokeratins in human enamel organ. The slow-growing nature of the lesion may cause the patients to tolerate the swelling for years until it produces an obvious deformity.

The treatment of choice was a surgical management of this tumor.